STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHM00413.1Cys/Met metabolism PLP-dependent enzyme; KEGG: bln:Blon_0757 3.1e-125 cysteine synthase K01740; Psort location: Cytoplasmic, score: 9.97. (434 aa)    
Predicted Functional Partners:
metAA
Putative homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
 
 
 0.989
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.951
EHL96173.1
Methionine synthase, vitamin-B12 independent; KEGG: llm:llmg_1849 3.8e-120 metE2; hypothetical protein K00549; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.933
EHL98943.1
KEGG: lrh:LGG_02155 1.1e-104 thrA; homoserine dehydrogenase; K00003 homoserine dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.924
EHM00406.1
KEGG: lki:LKI_03365 2.3e-122 cystathionine beta-lyase; K01760 cystathionine beta-lyase; Psort location: Cytoplasmic, score: 9.97.
 
 
0.914
EHM00860.1
Putative cystathionine beta-lyase PatB; KEGG: lcr:LCRIS_00748 2.3e-115 patB; aminotransferase; K14155 cystathione beta-lyase; Psort location: Cytoplasmic, score: 9.26.
   
 0.907
EHL95343.1
KEGG: lpj:JDM1_2042 8.3e-189 metY; O-acetylhomoserine (thiol)-lyase; K01740 O-acetylhomoserine (thiol)-lyase; Psort location: Cytoplasmic, score: 9.26.
  
  
 
0.906
luxS
S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
     
 0.900
EHL98934.1
Putative homocysteine S-methyltransferase; KEGG: lpl:lp_1298 1.8e-81 mmuM; homocysteine methyltransferase K00547; Psort location: Cytoplasmic, score: 9.26.
     
 0.898
ilvA
Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 
  0.891
Your Current Organism:
Lactobacillus parafarraginis
NCBI taxonomy Id: 797515
Other names: L. parafarraginis F0439, Lactobacillus parafarraginis F0439, Lactobacillus parafarraginis str. F0439, Lactobacillus parafarraginis strain F0439, Lactobacillus sp. oral taxon 418 str. F0439
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