STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sbcDExonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (384 aa)    
Predicted Functional Partners:
EHM00192.1
KEGG: lsl:LSL_1369 8.9e-137 sbcC; exonuclease K03546; Psort location: Cytoplasmic, score: 9.26.
 
 0.998
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 0.994
EHL95925.1
KEGG: lre:Lreu_0760 1.5e-104 ATP-dependent DNA helicase RecQ; K03654 ATP-dependent DNA helicase RecQ; Psort location: Cytoplasmic, score: 9.97.
  
 0.761
EHM00148.1
KEGG: ppe:PEPE_0562 6.7e-226 ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 9.97.
   
 0.729
dinG
DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease.
  
 0.665
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.631
EHL98723.1
Hypothetical protein; KEGG: cno:NT01CX_0936 3.5e-149 DNA repair helicase, truncation, putative; K10844 DNA excision repair protein ERCC-2; Psort location: Cytoplasmic, score: 9.97.
   
 0.599
addA
ATP-dependent nuclease subunit A; ATP-dependent DNA helicase.
  
  
 0.487
smc
Segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
  
 
 0.483
recD2
Helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.
   
 
 0.475
Your Current Organism:
Lactobacillus parafarraginis
NCBI taxonomy Id: 797515
Other names: L. parafarraginis F0439, Lactobacillus parafarraginis F0439, Lactobacillus parafarraginis str. F0439, Lactobacillus parafarraginis strain F0439, Lactobacillus sp. oral taxon 418 str. F0439
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