STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHM00041.1Spore protein SP21 domain protein; KEGG: apb:SAR116_0129 9.3e-07 molecular chaperone K13993; Belongs to the small heat shock protein (HSP20) family. (140 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 
 0.695
EHL99171.1
Negative regulator of genetic competence ClpC/MecB; KEGG: saa:SAUSA300_0510 9.4e-236 clpC; endopeptidase K03696; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family.
  
 
 0.681
EHL97432.1
Hypothetical protein; KEGG: sax:USA300HOU_2542 5.9e-19 clp; endopeptidase Clp K04086.
 
 
 0.675
EHL95939.1
Putative chaperone protein ClpB; KEGG: sax:USA300HOU_0933 4.9e-168 clpB; endopeptidase ClpB K03695; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family.
  
 
 0.656
EHL99280.1
Negative regulator of genetic competence ClpC/MecB; KEGG: snc:HMPREF0837_11672 1.8e-234 clpE; ATP dependent protease K03697; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family.
  
 
 0.632
EHL98543.1
ATPase family; KEGG: snc:HMPREF0837_11672 6.6e-38 clpE; ATP dependent protease K03697; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.632
EHL98544.1
ATPase, AAA family; KEGG: snc:HMPREF0837_11672 1.8e-131 clpE; ATP dependent protease K03697; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family.
  
 
 0.632
EHL97805.1
Putative ATP-dependent Clp protease ATP-binding subunit ClpE; KEGG: sax:USA300HOU_2542 9.4e-220 clp; endopeptidase Clp K04086; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family.
  
 
 0.632
EHL95938.1
ATPase family; KEGG: sax:USA300HOU_0933 3.4e-73 clpB; endopeptidase ClpB K03695; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.632
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
  
  
 0.568
Your Current Organism:
Lactobacillus parafarraginis
NCBI taxonomy Id: 797515
Other names: L. parafarraginis F0439, Lactobacillus parafarraginis F0439, Lactobacillus parafarraginis str. F0439, Lactobacillus parafarraginis strain F0439, Lactobacillus sp. oral taxon 418 str. F0439
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.