STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHL98927.1Aminotransferase, class I/II; KEGG: lre:Lreu_1902 1.1e-120 aromatic amino acid aminotransferase / 2-aminoadipate aminotransferase; Psort location: Cytoplasmic, score: 9.97. (416 aa)    
Predicted Functional Partners:
EHL97554.1
Putative L-lactate oxidase; KEGG: lpl:lp_3586 1.0e-149 lox; lactate oxidase K00119; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.717
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
   
 0.673
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
 
 0.669
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
   
 
 0.669
EHM00017.1
KEGG: lfe:LAF_1105 5.9e-60 prephenate dehydrogenase; K04517 prephenate dehydrogenase.
    
 0.662
dltA
D-alanine--poly(phosphoribitol) ligase, subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]
   
 
 0.660
EHM00423.1
Prephenate dehydratase; KEGG: clj:CLJU_c25500 3.2e-45 pheA1; prephenate dehydratase; Psort location: Cytoplasmic, score: 9.26.
    
 0.658
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
   
 
 0.649
EHL97579.1
Glutamine amidotransferase, class I; KEGG: ere:EUBREC_2979 2.9e-51 anthranilate/para-aminobenzoate synthase component II, TrpG; K01658 anthranilate synthase component II; Psort location: Cytoplasmic, score: 9.26.
   
 
 0.644
trpC
KEGG: lcb:LCABL_00750 3.1e-102 trpC; indole-3-glycerol-phosphate synthase K01609; Psort location: Cytoplasmic, score: 9.97; Belongs to the TrpC family.
   
 
 0.640
Your Current Organism:
Lactobacillus parafarraginis
NCBI taxonomy Id: 797515
Other names: L. parafarraginis F0439, Lactobacillus parafarraginis F0439, Lactobacillus parafarraginis str. F0439, Lactobacillus parafarraginis strain F0439, Lactobacillus sp. oral taxon 418 str. F0439
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.