STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHL98721.1KEGG: lbr:LVIS_2298 1.1e-49 signal peptidase I; K03100 signal peptidase I; Psort location: CytoplasmicMembrane, score: 9.82; Belongs to the peptidase S26 family. (216 aa)    
Predicted Functional Partners:
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
 
 0.582
EHL95992.1
RIP metalloprotease RseP; KEGG: lbr:LVIS_1343 3.0e-143 membrane-associated Zn-dependent protease 1; K01417; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.581
EHL95969.1
RelA/SpoT family protein; KEGG: lbr:LVIS_0728 1.9e-166 guanosine polyphosphate pyrophosphohydrolase/synthetase; K00951 GTP pyrophosphokinase; Psort location: Cytoplasmic, score: 8.96.
 
    0.539
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
    0.528
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
   0.518
EHL97918.1
Membrane protein insertase, YidC/Oxa1 family; KEGG: apb:SAR116_1502 1.3e-09 60 kDa inner membrane insertion protein K03217; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.481
EHL99763.1
Putative glutamate synthase [NADPH], large subunit; KEGG: lca:LSEI_2556 0. glutamate synthase domain-containing 3; K00265 glutamate synthase (NADPH/NADH) large chain; Psort location: Cytoplasmic, score: 9.26.
     
 0.453
EHL95970.1
HD domain protein; KEGG: lbr:LVIS_0728 2.1e-121 guanosine polyphosphate pyrophosphohydrolase/synthetase; K00951 GTP pyrophosphokinase; Psort location: Cytoplasmic, score: 8.96.
 
    0.420
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
  
  
 0.418
EHL96895.1
Peptidase S24-like protein; KEGG: mcl:MCCL_1543 2.6e-11 hypothetical protein; K01356 repressor LexA; Psort location: Cytoplasmic, score: 8.96.
  
 
  0.417
Your Current Organism:
Lactobacillus parafarraginis
NCBI taxonomy Id: 797515
Other names: L. parafarraginis F0439, Lactobacillus parafarraginis F0439, Lactobacillus parafarraginis str. F0439, Lactobacillus parafarraginis strain F0439, Lactobacillus sp. oral taxon 418 str. F0439
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.