STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHL97822.1Sortase family protein; Psort location: CytoplasmicMembrane, score: 9.82. (242 aa)    
Predicted Functional Partners:
lspA
Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
      
 0.572
EHL97821.1
Transporter, major facilitator family protein; KEGG: apb:SAR116_1122 1.2e-11 tetracycline resistance protein; Psort location: CytoplasmicMembrane, score: 10.00.
       0.564
EHM01476.1
Hypothetical protein; KEGG: lbr:LVIS_1489 2.1e-26 membrane carboxypeptidase (penicillin-binding protein); K12555 penicillin-binding protein 2A.
  
   
 0.506
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.506
EHM00512.1
Putative protein DltB; Could be involved in the transport of activated D-alanine through the membrane.
  
   
 0.490
EHM00489.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00.
  
     0.471
EHL98511.1
Hypothetical protein.
 
  
 0.458
EHL97150.1
single-stranded-DNA-specific exonuclease RecJ; KEGG: lbr:LVIS_1377 5.6e-190 single-stranded DNA-specific exonuclease; K07462 single-stranded-DNA-specific exonuclease; Psort location: Cytoplasmic, score: 9.26.
     
 0.453
EHL97918.1
Membrane protein insertase, YidC/Oxa1 family; KEGG: apb:SAR116_1502 1.3e-09 60 kDa inner membrane insertion protein K03217; Psort location: CytoplasmicMembrane, score: 10.00.
 
   
 0.438
rpoE
DNA-directed RNA polymerase, delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family.
  
     0.437
Your Current Organism:
Lactobacillus parafarraginis
NCBI taxonomy Id: 797515
Other names: L. parafarraginis F0439, Lactobacillus parafarraginis F0439, Lactobacillus parafarraginis str. F0439, Lactobacillus parafarraginis strain F0439, Lactobacillus sp. oral taxon 418 str. F0439
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