STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHL97133.1Guanine/hypoxanthine permease PbuG; KEGG: btk:BT9727_0241 7.3e-126 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; Psort location: CytoplasmicMembrane, score: 10.00. (451 aa)    
Predicted Functional Partners:
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
  
  
 0.563
purH
KEGG: lpl:lp_2720 1.5e-191 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.554
EHL97134.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00.
       0.551
EHL97132.1
Hypothetical protein; KEGG: lcr:LCRIS_00478 3.3e-185 lhr; ATP-dependent helicase; K03724 ATP-dependent helicase Lhr and Lhr-like helicase; Psort location: Cytoplasmic, score: 8.96.
       0.526
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
    0.517
purD
KEGG: lpl:lp_2719 3.5e-110 purD; phosphoribosylamine--glycine ligase K01945; Psort location: Cytoplasmic, score: 9.97; Belongs to the GARS family.
  
  
 0.511
purL
Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...]
  
  
 0.497
purC
KEGG: lpj:JDM1_2186 5.9e-76 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase; K01923 phosphoribosylaminoimidazole-succinocarboxamide synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the SAICAR synthetase family.
  
  
 0.495
EHM00197.1
Macro domain protein; KEGG: noc:Noc_1830 7.5e-21 Appr-1-p processing; Psort location: Cytoplasmic, score: 8.96.
      0.466
purM
Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: lpl:lp_2722 4.4e-103 purM; phosphoribosylaminoimidazole synthetase K01933; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.463
Your Current Organism:
Lactobacillus parafarraginis
NCBI taxonomy Id: 797515
Other names: L. parafarraginis F0439, Lactobacillus parafarraginis F0439, Lactobacillus parafarraginis str. F0439, Lactobacillus parafarraginis strain F0439, Lactobacillus sp. oral taxon 418 str. F0439
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.