STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHL95925.1KEGG: lre:Lreu_0760 1.5e-104 ATP-dependent DNA helicase RecQ; K03654 ATP-dependent DNA helicase RecQ; Psort location: Cytoplasmic, score: 9.97. (483 aa)    
Predicted Functional Partners:
EHL97945.1
Toprim domain protein; KEGG: lpl:pWCFS103_22 6.7e-123 traI; DNA topoisomerase; K03169 DNA topoisomerase III; Psort location: Cytoplasmic, score: 9.26.
 
 
 0.979
EHL95926.1
KEGG: bce:BC1484 0.0019 hypothetical protein K01529; Psort location: CytoplasmicMembrane, score: 9.82.
 
 
 0.971
EHL97150.1
single-stranded-DNA-specific exonuclease RecJ; KEGG: lbr:LVIS_1377 5.6e-190 single-stranded DNA-specific exonuclease; K07462 single-stranded-DNA-specific exonuclease; Psort location: Cytoplasmic, score: 9.26.
   
 0.949
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
 0.949
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.929
EHL99220.1
KEGG: lpj:JDM1_0939 6.2e-271 pcrA; ATP-dependent DNA helicase PcrA; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97.
 
 0.921
cshA
DEAD-box ATP-dependent RNA helicase CshA; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily.
 
0.909
EHL97905.1
Hypothetical protein; KEGG: lpl:pWCFS103_22 8.3e-27 traI; DNA topoisomerase; K03169 DNA topoisomerase III.
   
 0.832
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.828
EHM00192.1
KEGG: lsl:LSL_1369 8.9e-137 sbcC; exonuclease K03546; Psort location: Cytoplasmic, score: 9.26.
 
 0.820
Your Current Organism:
Lactobacillus parafarraginis
NCBI taxonomy Id: 797515
Other names: L. parafarraginis F0439, Lactobacillus parafarraginis F0439, Lactobacillus parafarraginis str. F0439, Lactobacillus parafarraginis strain F0439, Lactobacillus sp. oral taxon 418 str. F0439
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