STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
polCDNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1437 aa)    
Predicted Functional Partners:
EHL97559.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 0.932
dnaX
DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.932
EHM00363.1
KEGG: lpj:JDM1_1783 8.4e-93 holA; DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta; Psort location: Cytoplasmic, score: 8.96.
    
 0.925
EHL96652.1
KEGG: lbr:LVIS_0606 9.4e-78 DNA polymerase III subunit delta' K02341; Psort location: Cytoplasmic, score: 9.26.
   
 0.917
EHL95935.1
KEGG: lbr:LVIS_0763 0. DNA polymerase III, alpha subunit; K02337 DNA polymerase III subunit alpha; Psort location: Cytoplasmic, score: 9.26.
    
0.916
EHL97973.1
Exonuclease; KEGG: lbr:LVIS_0678 3.3e-66 DNA polymerase III, epsilon subunit related 3'-5' exonuclease; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.26.
    
0.878
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
 
    0.759
EHL95987.1
Hypothetical protein.
 
    0.732
EHM01442.1
Hydrolase, HD family; KEGG: clo:HMPREF0868_0799 1.6e-18 nadD; nicotinate-nucleotide adenylyltransferase K00969; Psort location: Cytoplasmic, score: 8.96.
  
     0.730
rimP
Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
 
  
 0.723
Your Current Organism:
Lactobacillus parafarraginis
NCBI taxonomy Id: 797515
Other names: L. parafarraginis F0439, Lactobacillus parafarraginis F0439, Lactobacillus parafarraginis str. F0439, Lactobacillus parafarraginis strain F0439, Lactobacillus sp. oral taxon 418 str. F0439
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