STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHL95792.1KEGG: lbr:LVIS_1363 2.5e-109 3-hydroxy-3-methylglutaryl CoA synthase; K01641 hydroxymethylglutaryl-CoA synthase; Psort location: CytoplasmicMembrane, score: 9.82. (424 aa)    
Predicted Functional Partners:
EHM00938.1
hydroxymethylglutaryl-CoA reductase, degradative; KEGG: lbr:LVIS_0450 7.7e-99 hydroxymethylglutaryl-CoA reductase; K00021 3-hydroxy-3-methylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.
 
 0.999
EHL98208.1
KEGG: lca:LSEI_1787 1.7e-110 acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase; Psort location: Cytoplasmic, score: 9.97; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.999
EHL95896.1
Diphosphomevalonate decarboxylase; KEGG: lbr:LVIS_0859 2.5e-93 phosphomevalonate kinase; K01597 diphosphomevalonate decarboxylase.
 
 
 0.934
EHL95895.1
Mevalonate kinase; KEGG: lbr:LVIS_0858 1.1e-58 mevalonate kinase; K00869 mevalonate kinase.
 
 
 0.922
EHL95897.1
Phosphomevalonate kinase; KEGG: lsa:LSA0906 6.5e-125 mvaK2; phosphomevalonate kinase K00938; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.912
EHL95193.1
Putative 2-methylcitrate synthase; KEGG: ste:STER_1245 6.6e-77 citrate synthase K01647; Psort location: Cytoplasmic, score: 9.97.
    
 0.910
EHM00706.1
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
   
 
  0.898
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
 
 0.880
dltC
D-alanine--poly(phosphoribitol) ligase, subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
  
 0.834
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 0.834
Your Current Organism:
Lactobacillus parafarraginis
NCBI taxonomy Id: 797515
Other names: L. parafarraginis F0439, Lactobacillus parafarraginis F0439, Lactobacillus parafarraginis str. F0439, Lactobacillus parafarraginis strain F0439, Lactobacillus sp. oral taxon 418 str. F0439
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