STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiIThiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (405 aa)    
Predicted Functional Partners:
EHL95623.1
Aminotransferase, class V.
 0.995
EHM00740.1
Putative cysteine desulfurase; KEGG: lbr:LVIS_1436 1.7e-149 cysteine sulfinate desulfinase/cysteine desulfurase; K04487 cysteine desulfurase; Psort location: Cytoplasmic, score: 9.97.
 0.970
EHL96075.1
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
   
    0.934
thiG
Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
     
 0.922
EHL97091.1
Aminotransferase, class V; KEGG: lmn:LM5578_2224 3.4e-73 hypothetical protein; K04487 cysteine desulfurase; Psort location: Cytoplasmic, score: 9.26.
  
 0.821
mnmA
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
 
 
 0.808
EHL95604.1
Competence/damage-inducible protein CinA domain protein; Belongs to the CinA family.
      0.801
EHL95151.1
ThiF family protein; KEGG: ppy:PPE_03281 5.4e-43 adenylyltransferase ThiF; Psort location: Cytoplasmic, score: 9.26.
    
 0.722
EHL95899.1
NOL1/NOP2/sun family protein; KEGG: lbr:LVIS_0862 1.7e-133 tRNA and rRNA cytosine-C5-methylase; K00599; Psort location: Cytoplasmic, score: 9.97.
  
    0.703
ezrA
Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
       0.640
Your Current Organism:
Lactobacillus parafarraginis
NCBI taxonomy Id: 797515
Other names: L. parafarraginis F0439, Lactobacillus parafarraginis F0439, Lactobacillus parafarraginis str. F0439, Lactobacillus parafarraginis strain F0439, Lactobacillus sp. oral taxon 418 str. F0439
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