STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHO54442.1Hypothetical protein; KEGG: rru:Rru_A3627 5.0e-10 chromosome segregation ATPase K03496. (195 aa)    
Predicted Functional Partners:
EHO54092.1
Stage 0 sporulation protein J; KEGG: pub:SAR11_0354 1.1e-42 parB; chromosome partitioning protein K03497; Psort location: Cytoplasmic, score: 9.97; Belongs to the ParB family.
 
 
 0.942
dnaA
Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
  
 
 0.634
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.552
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.551
EHO51076.1
Hypothetical protein.
  
     0.499
EHO54147.1
Hypothetical protein; Psort location: OuterMembrane, score: 9.49.
    
   0.485
EHO53537.1
Hypothetical protein.
    
   0.485
EHO53535.1
Hypothetical protein; KEGG: spb:M28_Spy1898 3.4e-05 htrA; protease Do K01362; Psort location: Extracellular, score: 9.64.
    
   0.485
EHO53139.1
Hypothetical protein; KEGG: pjd:Pjdr2_5076 8.9e-59 alpha-L-fucosidase; Psort location: Cytoplasmic, score: 8.96.
    
   0.485
EHO52470.1
Hypothetical protein; KEGG: pjd:Pjdr2_5076 1.8e-55 alpha-L-fucosidase; Psort location: Cytoplasmic, score: 8.96.
    
   0.485
Your Current Organism:
Lactobacillus kisonensis
NCBI taxonomy Id: 797516
Other names: L. kisonensis F0435, Lactobacillus kisonensis F0435, Lactobacillus kisonensis str. F0435, Lactobacillus kisonensis strain F0435, Lactobacillus sp. oral taxon 424 str. F0435
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