STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHO54272.1Hypothetical protein; KEGG: hpa:HPAG1_1423 2.3e-51 hemolysin domain-containing protein K00088; Psort location: CytoplasmicMembrane, score: 9.97. (462 aa)    
Predicted Functional Partners:
EHO51636.1
KEGG: lbr:LVIS_1759 1.1e-99 guaA; GMP synthase K01951; Psort location: Cytoplasmic, score: 9.26; overlaps another CDS with the same product name.
  
 
 0.944
EHO51637.1
KEGG: ppe:PEPE_0412 4.1e-123 guaA; GMP synthase K01951; Psort location: Cytoplasmic, score: 9.97; overlaps another CDS with the same product name.
  
 
 0.944
EHO50905.1
KEGG: lbr:LVIS_0522 3.1e-63 hypoxanthine-guanine phosphoribosyltransferase; K00760 hypoxanthine phosphoribosyltransferase; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
  0.620
mprF-2
Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
  
     0.611
EHO54098.1
IMP dehydrogenase / GMP reductase domain protein; KEGG: lrl:LC705_00240 1.1e-33 guaB; inosine-5'-monophosphate dehydrogenase; K00088 IMP dehydrogenase; Psort location: Cytoplasmic, score: 9.26.
  
 
  0.546
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.545
EHO48593.1
Thioredoxin; KEGG: lwe:lwe1188 4.3e-34 trxA; thioredoxin K03671; Psort location: Cytoplasmic, score: 9.26; Belongs to the thioredoxin family.
  
    0.540
EHO48567.1
Ser/Thr phosphatase family protein; KEGG: ldb:Ldb1591 1.3e-105 putative 5'-nucleotidase K01081; Psort location: Cytoplasmic, score: 8.96; Belongs to the 5'-nucleotidase family.
 
  
  0.512
ybeY
Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.511
purH
KEGG: lpl:lp_2720 4.3e-192 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602; Psort location: Cytoplasmic, score: 9.97.
    
  0.510
Your Current Organism:
Lactobacillus kisonensis
NCBI taxonomy Id: 797516
Other names: L. kisonensis F0435, Lactobacillus kisonensis F0435, Lactobacillus kisonensis str. F0435, Lactobacillus kisonensis strain F0435, Lactobacillus sp. oral taxon 424 str. F0435
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.