| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EHO47591.1 | EHO49474.1 | HMPREF9104_03063 | HMPREF9104_02536 | Homocysteine S-methyltransferase; KEGG: ckr:CKR_0880 4.1e-46 hypothetical protein; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.26. | O-acetylserine dependent cystathionine beta-synthase; KEGG: lrl:pLC705_00039 1.8e-129 cysK; cysteine synthase (beta-pyrazolylalanine synthase) (beta-PA/CSase) (L-mimosine synthase) (O-acetylserine sulfhydrylase) (CSase) (OAS-TL); K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.26. | 0.977 |
| EHO47591.1 | EHO50287.1 | HMPREF9104_03063 | HMPREF9104_02094 | Homocysteine S-methyltransferase; KEGG: ckr:CKR_0880 4.1e-46 hypothetical protein; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.26. | KEGG: lki:LKI_03365 3.5e-119 cystathionine beta-lyase; K01760 cystathionine beta-lyase; Psort location: Cytoplasmic, score: 9.97. | 0.978 |
| EHO47591.1 | EHO51765.1 | HMPREF9104_03063 | HMPREF9104_01316 | Homocysteine S-methyltransferase; KEGG: ckr:CKR_0880 4.1e-46 hypothetical protein; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.26. | KEGG: lca:LSEI_2151 2.2e-101 homoserine dehydrogenase; K00003 homoserine dehydrogenase; Psort location: Cytoplasmic, score: 9.97. | 0.990 |
| EHO47591.1 | EHO52627.1 | HMPREF9104_03063 | HMPREF9104_00895 | Homocysteine S-methyltransferase; KEGG: ckr:CKR_0880 4.1e-46 hypothetical protein; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.26. | Putative cystathionine beta-lyase PatB; KEGG: lcr:LCRIS_00748 3.8e-136 patB; aminotransferase; K14155 cystathione beta-lyase; Psort location: Cytoplasmic, score: 9.26. | 0.910 |
| EHO47591.1 | EHO53778.1 | HMPREF9104_03063 | HMPREF9104_00406 | Homocysteine S-methyltransferase; KEGG: ckr:CKR_0880 4.1e-46 hypothetical protein; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.26. | Methionine synthase, vitamin-B12 independent; KEGG: pam:PANA_0956 5.5e-89 yxjG; YxjG; K00549 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 8.96. | 0.975 |
| EHO47591.1 | EHO54111.1 | HMPREF9104_03063 | HMPREF9104_00234 | Homocysteine S-methyltransferase; KEGG: ckr:CKR_0880 4.1e-46 hypothetical protein; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.26. | Cys/Met metabolism PLP-dependent enzyme; KEGG: bln:Blon_0757 4.1e-36 cysteine synthase K01740; Psort location: Cytoplasmic, score: 9.97. | 0.955 |
| EHO47591.1 | EHO54112.1 | HMPREF9104_03063 | HMPREF9104_00235 | Homocysteine S-methyltransferase; KEGG: ckr:CKR_0880 4.1e-46 hypothetical protein; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.26. | Cys/Met metabolism PLP-dependent enzyme; KEGG: bln:Blon_0757 1.2e-77 cysteine synthase K01740; Psort location: Cytoplasmic, score: 9.97. | 0.955 |
| EHO47591.1 | luxS | HMPREF9104_03063 | HMPREF9104_02540 | Homocysteine S-methyltransferase; KEGG: ckr:CKR_0880 4.1e-46 hypothetical protein; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.26. | S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.980 |
| EHO47591.1 | metAA | HMPREF9104_03063 | HMPREF9104_00956 | Homocysteine S-methyltransferase; KEGG: ckr:CKR_0880 4.1e-46 hypothetical protein; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.26. | Putative homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.911 |
| EHO47591.1 | metE | HMPREF9104_03063 | HMPREF9104_02541 | Homocysteine S-methyltransferase; KEGG: ckr:CKR_0880 4.1e-46 hypothetical protein; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.26. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.991 |
| EHO49474.1 | EHO47591.1 | HMPREF9104_02536 | HMPREF9104_03063 | O-acetylserine dependent cystathionine beta-synthase; KEGG: lrl:pLC705_00039 1.8e-129 cysK; cysteine synthase (beta-pyrazolylalanine synthase) (beta-PA/CSase) (L-mimosine synthase) (O-acetylserine sulfhydrylase) (CSase) (OAS-TL); K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.26. | Homocysteine S-methyltransferase; KEGG: ckr:CKR_0880 4.1e-46 hypothetical protein; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.26. | 0.977 |
| EHO49474.1 | EHO50287.1 | HMPREF9104_02536 | HMPREF9104_02094 | O-acetylserine dependent cystathionine beta-synthase; KEGG: lrl:pLC705_00039 1.8e-129 cysK; cysteine synthase (beta-pyrazolylalanine synthase) (beta-PA/CSase) (L-mimosine synthase) (O-acetylserine sulfhydrylase) (CSase) (OAS-TL); K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.26. | KEGG: lki:LKI_03365 3.5e-119 cystathionine beta-lyase; K01760 cystathionine beta-lyase; Psort location: Cytoplasmic, score: 9.97. | 0.983 |
| EHO49474.1 | EHO51765.1 | HMPREF9104_02536 | HMPREF9104_01316 | O-acetylserine dependent cystathionine beta-synthase; KEGG: lrl:pLC705_00039 1.8e-129 cysK; cysteine synthase (beta-pyrazolylalanine synthase) (beta-PA/CSase) (L-mimosine synthase) (O-acetylserine sulfhydrylase) (CSase) (OAS-TL); K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.26. | KEGG: lca:LSEI_2151 2.2e-101 homoserine dehydrogenase; K00003 homoserine dehydrogenase; Psort location: Cytoplasmic, score: 9.97. | 0.596 |
| EHO49474.1 | EHO52627.1 | HMPREF9104_02536 | HMPREF9104_00895 | O-acetylserine dependent cystathionine beta-synthase; KEGG: lrl:pLC705_00039 1.8e-129 cysK; cysteine synthase (beta-pyrazolylalanine synthase) (beta-PA/CSase) (L-mimosine synthase) (O-acetylserine sulfhydrylase) (CSase) (OAS-TL); K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.26. | Putative cystathionine beta-lyase PatB; KEGG: lcr:LCRIS_00748 3.8e-136 patB; aminotransferase; K14155 cystathione beta-lyase; Psort location: Cytoplasmic, score: 9.26. | 0.964 |
| EHO49474.1 | EHO53778.1 | HMPREF9104_02536 | HMPREF9104_00406 | O-acetylserine dependent cystathionine beta-synthase; KEGG: lrl:pLC705_00039 1.8e-129 cysK; cysteine synthase (beta-pyrazolylalanine synthase) (beta-PA/CSase) (L-mimosine synthase) (O-acetylserine sulfhydrylase) (CSase) (OAS-TL); K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.26. | Methionine synthase, vitamin-B12 independent; KEGG: pam:PANA_0956 5.5e-89 yxjG; YxjG; K00549 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 8.96. | 0.961 |
| EHO49474.1 | EHO54111.1 | HMPREF9104_02536 | HMPREF9104_00234 | O-acetylserine dependent cystathionine beta-synthase; KEGG: lrl:pLC705_00039 1.8e-129 cysK; cysteine synthase (beta-pyrazolylalanine synthase) (beta-PA/CSase) (L-mimosine synthase) (O-acetylserine sulfhydrylase) (CSase) (OAS-TL); K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.26. | Cys/Met metabolism PLP-dependent enzyme; KEGG: bln:Blon_0757 4.1e-36 cysteine synthase K01740; Psort location: Cytoplasmic, score: 9.97. | 0.950 |
| EHO49474.1 | EHO54112.1 | HMPREF9104_02536 | HMPREF9104_00235 | O-acetylserine dependent cystathionine beta-synthase; KEGG: lrl:pLC705_00039 1.8e-129 cysK; cysteine synthase (beta-pyrazolylalanine synthase) (beta-PA/CSase) (L-mimosine synthase) (O-acetylserine sulfhydrylase) (CSase) (OAS-TL); K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.26. | Cys/Met metabolism PLP-dependent enzyme; KEGG: bln:Blon_0757 1.2e-77 cysteine synthase K01740; Psort location: Cytoplasmic, score: 9.97. | 0.959 |
| EHO49474.1 | luxS | HMPREF9104_02536 | HMPREF9104_02540 | O-acetylserine dependent cystathionine beta-synthase; KEGG: lrl:pLC705_00039 1.8e-129 cysK; cysteine synthase (beta-pyrazolylalanine synthase) (beta-PA/CSase) (L-mimosine synthase) (O-acetylserine sulfhydrylase) (CSase) (OAS-TL); K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.26. | S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.980 |
| EHO49474.1 | metAA | HMPREF9104_02536 | HMPREF9104_00956 | O-acetylserine dependent cystathionine beta-synthase; KEGG: lrl:pLC705_00039 1.8e-129 cysK; cysteine synthase (beta-pyrazolylalanine synthase) (beta-PA/CSase) (L-mimosine synthase) (O-acetylserine sulfhydrylase) (CSase) (OAS-TL); K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.26. | Putative homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.981 |
| EHO49474.1 | metE | HMPREF9104_02536 | HMPREF9104_02541 | O-acetylserine dependent cystathionine beta-synthase; KEGG: lrl:pLC705_00039 1.8e-129 cysK; cysteine synthase (beta-pyrazolylalanine synthase) (beta-PA/CSase) (L-mimosine synthase) (O-acetylserine sulfhydrylase) (CSase) (OAS-TL); K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.26. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.961 |