STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (374 aa)    
Predicted Functional Partners:
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
 
 0.904
rpmA
Ribosomal protein L27; KEGG: apb:SAR116_1855 1.4e-19 ribosomal protein L27 K02899; Psort location: Cytoplasmic, score: 9.26; Belongs to the bacterial ribosomal protein bL27 family.
  
  
 0.762
EHO53967.1
Putative cysteine desulfurase; KEGG: lbr:LVIS_1436 5.9e-147 cysteine sulfinate desulfinase/cysteine desulfurase; K04487 cysteine desulfurase; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.693
ddl
D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
  
  
 0.685
pheT
KEGG: lbr:LVIS_1009 2.3e-271 pheT; phenylalanyl-tRNA synthetase subunit beta K01890; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.684
EHO48857.1
Riboflavin biosynthesis protein RibF; KEGG: lbr:LVIS_1332 2.0e-82 FAD synthase; K11753 riboflavin kinase / FMN adenylyltransferase; Psort location: Cytoplasmic, score: 9.97; Belongs to the ribF family.
 
    0.661
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
  
  
 0.656
mnmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
 
 0.654
EHO51149.1
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.608
EHO50905.1
KEGG: lbr:LVIS_0522 3.1e-63 hypoxanthine-guanine phosphoribosyltransferase; K00760 hypoxanthine phosphoribosyltransferase; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
   
 
 0.601
Your Current Organism:
Lactobacillus kisonensis
NCBI taxonomy Id: 797516
Other names: L. kisonensis F0435, Lactobacillus kisonensis F0435, Lactobacillus kisonensis str. F0435, Lactobacillus kisonensis strain F0435, Lactobacillus sp. oral taxon 424 str. F0435
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