STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (178 aa)    
Predicted Functional Partners:
EHO51637.1
KEGG: ppe:PEPE_0412 4.1e-123 guaA; GMP synthase K01951; Psort location: Cytoplasmic, score: 9.97; overlaps another CDS with the same product name.
  
 0.995
ade
KEGG: lsa:LSA0088 2.2e-188 adeC1; adenine deaminase K01486; Psort location: Cytoplasmic, score: 8.96; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
   
 0.989
EHO52803.1
Adenylosuccinate lyase; KEGG: lpj:JDM1_2623 1.7e-174 purB; adenylosuccinate lyase; K01756 adenylosuccinate lyase; Psort location: Cytoplasmic, score: 9.97.
  
 0.987
purH
KEGG: lpl:lp_2720 4.3e-192 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602; Psort location: Cytoplasmic, score: 9.97.
  
 0.983
EHO54201.1
Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
   
 0.981
deoD
KEGG: lbr:LVIS_1593 9.2e-87 deoD; purine nucleoside phosphorylase; K03784 purine-nucleoside phosphorylase; Psort location: Cytoplasmic, score: 9.97.
     
 0.978
EHO49281.1
Guanylate kinase; KEGG: lpj:JDM1_0722 2.9e-51 gmk2; guanylate kinase; K00942 guanylate kinase; Psort location: Cytoplasmic, score: 9.26.
   
 
 0.975
guaC
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
  
 
 0.974
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
 
 0.973
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
 0.964
Your Current Organism:
Lactobacillus kisonensis
NCBI taxonomy Id: 797516
Other names: L. kisonensis F0435, Lactobacillus kisonensis F0435, Lactobacillus kisonensis str. F0435, Lactobacillus kisonensis strain F0435, Lactobacillus sp. oral taxon 424 str. F0435
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