STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHO51878.1Shikimate kinase; KEGG: lpj:JDM1_1697 2.2e-14 aroI; shikimate kinase; K00891 shikimate kinase; Psort location: Cytoplasmic, score: 8.96. (105 aa)    
Predicted Functional Partners:
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
 
 0.985
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
 
 0.979
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
 
 0.935
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.932
EHO51880.1
KEGG: lpl:lp_2034 2.0e-61 tyrA; prephenate dehydrogenase K04517.
 
 
 0.931
EHO51879.1
KEGG: lpj:JDM1_1697 1.5e-13 aroI; shikimate kinase; K00891 shikimate kinase; Psort location: Cytoplasmic, score: 9.26.
      0.917
EHO51859.1
Chorismate mutase; KEGG: sth:STH3129 2.3e-10 3-deoxy-7-phosphoheptulonate synthase K04516.
 
 
 0.839
EHO52103.1
KEGG: lpl:lp_1085 1.1e-117 aroA; 3-deoxy-7-phosphoheptulonate synthase K03856; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.720
EHO51229.1
KEGG: lpl:lp_0185 1.7e-124 pts1BCA; sucrose PTS, EIIBCA; K02808 PTS system, sucrose-specific IIA component; K02809 PTS system, sucrose-specific IIB component K02810; Psort location: CytoplasmicMembrane, score: 10.00.
    
 0.669
aroD
3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.
 
  
 0.664
Your Current Organism:
Lactobacillus kisonensis
NCBI taxonomy Id: 797516
Other names: L. kisonensis F0435, Lactobacillus kisonensis F0435, Lactobacillus kisonensis str. F0435, Lactobacillus kisonensis strain F0435, Lactobacillus sp. oral taxon 424 str. F0435
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