node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EHO47591.1 | EHO50925.1 | HMPREF9104_03063 | HMPREF9104_01719 | Homocysteine S-methyltransferase; KEGG: ckr:CKR_0880 4.1e-46 hypothetical protein; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.26. | Methyltransferase domain protein; KEGG: lpl:lp_1533 5.9e-60 methyltransferase (putative) K00599. | 0.719 |
EHO47591.1 | glyA | HMPREF9104_03063 | HMPREF9104_02934 | Homocysteine S-methyltransferase; KEGG: ckr:CKR_0880 4.1e-46 hypothetical protein; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.26. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.973 |
EHO50925.1 | EHO47591.1 | HMPREF9104_01719 | HMPREF9104_03063 | Methyltransferase domain protein; KEGG: lpl:lp_1533 5.9e-60 methyltransferase (putative) K00599. | Homocysteine S-methyltransferase; KEGG: ckr:CKR_0880 4.1e-46 hypothetical protein; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.26. | 0.719 |
EHO50925.1 | EHO50927.1 | HMPREF9104_01719 | HMPREF9104_01721 | Methyltransferase domain protein; KEGG: lpl:lp_1533 5.9e-60 methyltransferase (putative) K00599. | Hydrolase, HD family; KEGG: mcp:MCAP_0529 3.6e-18 nadD; putative nicotinate-nucleotide adenylyltransferase K00969; Psort location: Cytoplasmic, score: 8.96. | 0.885 |
EHO50925.1 | EHO50928.1 | HMPREF9104_01719 | HMPREF9104_01722 | Methyltransferase domain protein; KEGG: lpl:lp_1533 5.9e-60 methyltransferase (putative) K00599. | Hypothetical protein; KEGG: lpj:JDM1_1283 1.1e-14 nadD; nicotinic acid mononucleotide adenylyltransferase; K00969 nicotinate-nucleotide adenylyltransferase. | 0.836 |
EHO50925.1 | EHO50929.1 | HMPREF9104_01719 | HMPREF9104_01723 | Methyltransferase domain protein; KEGG: lpl:lp_1533 5.9e-60 methyltransferase (putative) K00599. | Putative nicotinate-nucleotide adenylyltransferase; KEGG: lbr:LVIS_1029 3.0e-42 nadD; nicotinic acid mononucleotide adenylyltransferase; K00969 nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 9.26; Belongs to the NadD family. | 0.765 |
EHO50925.1 | EHO50930.1 | HMPREF9104_01719 | HMPREF9104_01724 | Methyltransferase domain protein; KEGG: lpl:lp_1533 5.9e-60 methyltransferase (putative) K00599. | RNA-binding protein, YhbY family. | 0.862 |
EHO50925.1 | EHO50931.1 | HMPREF9104_01719 | HMPREF9104_01725 | Methyltransferase domain protein; KEGG: lpl:lp_1533 5.9e-60 methyltransferase (putative) K00599. | Ribosome biogenesis GTPase YqeH; KEGG: lre:Lreu_1237 2.0e-137 GTP-binding protein YqeH K06948; Psort location: Cytoplasmic, score: 8.96. | 0.788 |
EHO50925.1 | EHO50932.1 | HMPREF9104_01719 | HMPREF9104_01726 | Methyltransferase domain protein; KEGG: lpl:lp_1533 5.9e-60 methyltransferase (putative) K00599. | HAD phosphatase, family IIIA; KEGG: spd:SPD_1560 7.0e-34 hypothetical protein K07015. | 0.785 |
EHO50925.1 | glyA | HMPREF9104_01719 | HMPREF9104_02934 | Methyltransferase domain protein; KEGG: lpl:lp_1533 5.9e-60 methyltransferase (putative) K00599. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.753 |
EHO50925.1 | rsfS | HMPREF9104_01719 | HMPREF9104_01720 | Methyltransferase domain protein; KEGG: lpl:lp_1533 5.9e-60 methyltransferase (putative) K00599. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.884 |
EHO50925.1 | tmcAL | HMPREF9104_01719 | HMPREF9104_01718 | Methyltransferase domain protein; KEGG: lpl:lp_1533 5.9e-60 methyltransferase (putative) K00599. | Hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. | 0.964 |
EHO50927.1 | EHO50925.1 | HMPREF9104_01721 | HMPREF9104_01719 | Hydrolase, HD family; KEGG: mcp:MCAP_0529 3.6e-18 nadD; putative nicotinate-nucleotide adenylyltransferase K00969; Psort location: Cytoplasmic, score: 8.96. | Methyltransferase domain protein; KEGG: lpl:lp_1533 5.9e-60 methyltransferase (putative) K00599. | 0.885 |
EHO50927.1 | EHO50928.1 | HMPREF9104_01721 | HMPREF9104_01722 | Hydrolase, HD family; KEGG: mcp:MCAP_0529 3.6e-18 nadD; putative nicotinate-nucleotide adenylyltransferase K00969; Psort location: Cytoplasmic, score: 8.96. | Hypothetical protein; KEGG: lpj:JDM1_1283 1.1e-14 nadD; nicotinic acid mononucleotide adenylyltransferase; K00969 nicotinate-nucleotide adenylyltransferase. | 0.962 |
EHO50927.1 | EHO50929.1 | HMPREF9104_01721 | HMPREF9104_01723 | Hydrolase, HD family; KEGG: mcp:MCAP_0529 3.6e-18 nadD; putative nicotinate-nucleotide adenylyltransferase K00969; Psort location: Cytoplasmic, score: 8.96. | Putative nicotinate-nucleotide adenylyltransferase; KEGG: lbr:LVIS_1029 3.0e-42 nadD; nicotinic acid mononucleotide adenylyltransferase; K00969 nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 9.26; Belongs to the NadD family. | 0.993 |
EHO50927.1 | EHO50930.1 | HMPREF9104_01721 | HMPREF9104_01724 | Hydrolase, HD family; KEGG: mcp:MCAP_0529 3.6e-18 nadD; putative nicotinate-nucleotide adenylyltransferase K00969; Psort location: Cytoplasmic, score: 8.96. | RNA-binding protein, YhbY family. | 0.884 |
EHO50927.1 | EHO50931.1 | HMPREF9104_01721 | HMPREF9104_01725 | Hydrolase, HD family; KEGG: mcp:MCAP_0529 3.6e-18 nadD; putative nicotinate-nucleotide adenylyltransferase K00969; Psort location: Cytoplasmic, score: 8.96. | Ribosome biogenesis GTPase YqeH; KEGG: lre:Lreu_1237 2.0e-137 GTP-binding protein YqeH K06948; Psort location: Cytoplasmic, score: 8.96. | 0.878 |
EHO50927.1 | EHO50932.1 | HMPREF9104_01721 | HMPREF9104_01726 | Hydrolase, HD family; KEGG: mcp:MCAP_0529 3.6e-18 nadD; putative nicotinate-nucleotide adenylyltransferase K00969; Psort location: Cytoplasmic, score: 8.96. | HAD phosphatase, family IIIA; KEGG: spd:SPD_1560 7.0e-34 hypothetical protein K07015. | 0.889 |
EHO50927.1 | rsfS | HMPREF9104_01721 | HMPREF9104_01720 | Hydrolase, HD family; KEGG: mcp:MCAP_0529 3.6e-18 nadD; putative nicotinate-nucleotide adenylyltransferase K00969; Psort location: Cytoplasmic, score: 8.96. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.968 |
EHO50927.1 | tmcAL | HMPREF9104_01721 | HMPREF9104_01718 | Hydrolase, HD family; KEGG: mcp:MCAP_0529 3.6e-18 nadD; putative nicotinate-nucleotide adenylyltransferase K00969; Psort location: Cytoplasmic, score: 8.96. | Hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. | 0.922 |