STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHO50905.1KEGG: lbr:LVIS_0522 3.1e-63 hypoxanthine-guanine phosphoribosyltransferase; K00760 hypoxanthine phosphoribosyltransferase; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (180 aa)    
Predicted Functional Partners:
EHO51636.1
KEGG: lbr:LVIS_1759 1.1e-99 guaA; GMP synthase K01951; Psort location: Cytoplasmic, score: 9.26; overlaps another CDS with the same product name.
  
 
 0.995
EHO51637.1
KEGG: ppe:PEPE_0412 4.1e-123 guaA; GMP synthase K01951; Psort location: Cytoplasmic, score: 9.97; overlaps another CDS with the same product name.
  
 
 0.995
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
 
 
 0.991
EHO54098.1
IMP dehydrogenase / GMP reductase domain protein; KEGG: lrl:LC705_00240 1.1e-33 guaB; inosine-5'-monophosphate dehydrogenase; K00088 IMP dehydrogenase; Psort location: Cytoplasmic, score: 9.26.
  
 
 0.985
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
 
 
 0.979
ade
KEGG: lsa:LSA0088 2.2e-188 adeC1; adenine deaminase K01486; Psort location: Cytoplasmic, score: 8.96; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
 
  
 0.977
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.971
ftsH
ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
  
 0.968
deoD
KEGG: lbr:LVIS_1593 9.2e-87 deoD; purine nucleoside phosphorylase; K03784 purine-nucleoside phosphorylase; Psort location: Cytoplasmic, score: 9.97.
     
 0.959
tadA
Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
  
 
 0.959
Your Current Organism:
Lactobacillus kisonensis
NCBI taxonomy Id: 797516
Other names: L. kisonensis F0435, Lactobacillus kisonensis F0435, Lactobacillus kisonensis str. F0435, Lactobacillus kisonensis strain F0435, Lactobacillus sp. oral taxon 424 str. F0435
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