STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proAGlutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (414 aa)    
Predicted Functional Partners:
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.999
EHO51172.1
KEGG: lbr:LVIS_0990 1.4e-211 glutamine synthetase; K01915 glutamine synthetase; Psort location: Cytoplasmic, score: 9.97.
     
 0.961
EHO50521.1
Putative phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...]
   
 
 0.888
EHO50522.1
KEGG: bse:Bsel_0693 2.6e-08 phosphoribosylformylglycinamidine synthase I K01952.
   
 
 0.888
EHO51855.1
Hypothetical protein; KEGG: lrl:LC705_00586 3.4e-13 gdhA; glutamate dehydrogenase; K00262 glutamate dehydrogenase (NADP+).
     
 0.875
EHO51856.1
KEGG: lpl:lp_1169 1.3e-133 gdh; glutamate dehydrogenase K00262; Psort location: OuterMembrane, score: 9.92; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.875
atpA
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
 
    
 0.870
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 
 0.793
sfsA
KEGG: sis:LS215_2903 2.0e-13 sugar fermentation stimulation protein A K06206; Psort location: Cytoplasmic, score: 9.97; Belongs to the SfsA family.
    
   0.672
EHO52500.1
Putative succinylornithine transaminase; KEGG: lfe:LAF_0723 3.1e-125 argD; acetylornithine aminotransferase; K00818 acetylornithine aminotransferase; Psort location: Cytoplasmic, score: 9.26.
   
 0.665
Your Current Organism:
Lactobacillus kisonensis
NCBI taxonomy Id: 797516
Other names: L. kisonensis F0435, Lactobacillus kisonensis F0435, Lactobacillus kisonensis str. F0435, Lactobacillus kisonensis strain F0435, Lactobacillus sp. oral taxon 424 str. F0435
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