STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHO49904.1Toxin-antitoxin system, toxin component, MazF family. (113 aa)    
Predicted Functional Partners:
EHO49903.1
Addiction module antitoxin, RelB/DinJ family.
 
    0.943
EHO51533.1
Addiction module antitoxin, RelB/DinJ family.
  
    0.768
EHO47569.1
Addiction module antitoxin, RelB/DinJ family; Psort location: Cytoplasmic, score: 8.96.
  
     0.760
EHO49905.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.82.
       0.488
EHO49902.1
Hypothetical protein; KEGG: ccv:CCV52592_1319 4.1e-20 S-adenosylmethionine synthetase K08996; Psort location: CytoplasmicMembrane, score: 10.00.
 
     0.435
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.421
EHO52271.1
comF family protein; KEGG: nde:NIDE1089 1.3e-07 putative phosphoribosyltransferase; Psort location: Cytoplasmic, score: 8.96.
   
    0.414
Your Current Organism:
Lactobacillus kisonensis
NCBI taxonomy Id: 797516
Other names: L. kisonensis F0435, Lactobacillus kisonensis F0435, Lactobacillus kisonensis str. F0435, Lactobacillus kisonensis strain F0435, Lactobacillus sp. oral taxon 424 str. F0435
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.