STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHO47971.1Adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase domain protein; KEGG: ssa:SSA_0489 2.8e-14 cobU; adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase, putative K02231. (73 aa)    
Predicted Functional Partners:
EHO47970.1
Adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase family protein; KEGG: lrf:LAR_1587 3.3e-27 cobinamide kinase/cobinamide phosphate guanylyltransferase CobU; K02231 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase.
     0.981
cobS
adenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
 
 0.975
EHO47995.1
CobD/CbiB protein; KEGG: lin:lin1155 1.8e-44 cobD; cobalamin biosynthesis protein; K02227 adenosylcobinamide-phosphate synthase CobD; Psort location: CytoplasmicMembrane, score: 10.00.
 
 
 0.902
EHO47996.1
CobD/CbiB protein; KEGG: lre:Lreu_1721 4.1e-36 adenosylcobinamide-phosphate synthase K02227; Psort location: CytoplasmicMembrane, score: 9.82.
 
 
 0.901
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
 
 0.898
EHO49998.1
ATP:cob(I)alamin adenosyltransferase; KEGG: efe:EFER_2020 1.3e-39 putative propanediol utilization protein: B12 related PduO, bifunctional ATP:cob(I)alamin adenosyltransferase/GlcG domain; Psort location: Cytoplasmic, score: 9.97.
    
 0.859
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 
 0.833
EHO47973.1
Porphobilinogen synthase; KEGG: lre:Lreu_1701 3.0e-129 delta-aminolevulinic acid dehydratase K01698; Psort location: Cytoplasmic, score: 9.97; Belongs to the ALAD family.
     
 0.831
hemL
Glutamate-1-semialdehyde-2,1-aminomutase; KEGG: lrf:LAR_1588 3.2e-164 glutamate-1-semialdehyde aminotransferase; K01845 glutamate-1-semialdehyde 2,1-aminomutase; Psort location: Cytoplasmic, score: 9.26.
     
 0.821
EHO47969.1
uroporphyrinogen-III synthase.
     
 0.788
Your Current Organism:
Lactobacillus kisonensis
NCBI taxonomy Id: 797516
Other names: L. kisonensis F0435, Lactobacillus kisonensis F0435, Lactobacillus kisonensis str. F0435, Lactobacillus kisonensis strain F0435, Lactobacillus sp. oral taxon 424 str. F0435
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.