STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrDUnannotated protein; Catalyzes the conversion of dihydroorotate to orotate. (313 aa)    
Predicted Functional Partners:
pyrK
Unannotated protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
 
 
 0.999
pyrC
Unannotated protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
 0.996
pyrE
Unannotated protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
 0.994
pyrF
Unannotated protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
 
  
 0.988
pyrB
Unannotated protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.988
carB-2
Unannotated protein; Belongs to the CarB family.
 
 
 0.985
FZC76_08040
Unannotated protein.
 
 0.970
carA-2
Unannotated protein; Belongs to the CarA family.
 
  
 0.964
FZC76_01885
Unannotated protein.
  
  
 0.919
carB
Unannotated protein.
 
 
 0.863
Your Current Organism:
Bacillus horikoshii
NCBI taxonomy Id: 79883
Other names: ATCC 700161, B. horikoshii, CIP 105300, DSM 8719, LMG 17946, LMG:17946, strain PN-121
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.