STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KMK77138.1Bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase; Regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)    
Predicted Functional Partners:
KMK77140.1
Aspartate carbamoyltransferase catalytic subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.982
KMK77141.1
Dihydroorotase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.974
KMK77139.1
Uracil permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.960
KMK77147.1
Orotate phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.947
KMK77146.1
Orotidine 5'-phosphate decarboxylase; Type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.946
KMK77145.1
Catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.871
KMK77143.1
Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.841
KMK77142.1
Carbamoyl phosphate synthase small subunit; Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.795
KMK77144.1
Dihydroorotate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.792
KMK75184.1
Dihydroorotate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.784
Your Current Organism:
Bacillus pseudalcaliphilus
NCBI taxonomy Id: 79884
Other names: ATCC 700166, B. pseudalcaliphilus, Bacillus pseudalcalophilus, CIP 105304, DSM 8725, LMG 17951, LMG:17951, strain PN-137
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.