STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KMK76929.1Serine/threonine protein kinase; Binds to sigma-B preventing the formation of an RNA polymerase holoenzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)    
Predicted Functional Partners:
KMK76930.1
RNA polymerase sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation; induced by heat shock, salt stress, oxidative stress, glucose limitation, oxygen limitation and entry into stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.994
KMK76928.1
Anti-sigma-factor antagonist; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.979
KMK76927.1
Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.971
KMK76931.1
Indirect negative regulator of sigma-B activity; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.962
KMK76925.1
RsbT antagonist protein RsbS; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.926
KMK76924.1
RsbT co-antagonist protein RsbRA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.924
KMK78117.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.880
KMK76108.1
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the prespore at the onset of sporulation. Interaction with spoIIAB inhibits sigma F activity throughout the cell before the formation of the asymmetric septum; after septation the interaction is confined to the mother cell, and sigma F activity is released in the prespore; Derived by automated computational analysis using gene prediction method: Protein [...]
  
 
 0.837
KMK75815.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.821
KMK75775.1
Anti-anti-sigma regulatory factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.810
Your Current Organism:
Bacillus pseudalcaliphilus
NCBI taxonomy Id: 79884
Other names: ATCC 700166, B. pseudalcaliphilus, Bacillus pseudalcalophilus, CIP 105304, DSM 8725, LMG 17951, LMG:17951, strain PN-137
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