STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pus10Putative tRNA pseudouridine synthase Pus10. (652 aa)    
Predicted Functional Partners:
fam206a
UPF0436 protein C9orf6 homolog.
    
   0.804
PUS7
Pseudouridylate synthase 7-like protein.
   
  
 0.673
nop10
H/ACA ribonucleoprotein complex subunit 3.
     
 0.657
Trmt1
tRNA (guanine(26)-N(2))-dimethyltransferase.
      
 0.637
trmt5
tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family.
   
  
 0.590
RPUSD1
RNA pseudouridylate synthase domain-containing protein 1.
      
 0.565
PUS1
tRNA pseudouridine synthase A.
   
  
 0.563
PUS3
tRNA pseudouridine(38/39) synthase.
   
  
 0.530
DKC1
H/ACA ribonucleoprotein complex subunit 4.
   
  
 0.530
Thumpd2
THUMP domain-containing protein 2.
      
 0.530
Your Current Organism:
Clonorchis sinensis
NCBI taxonomy Id: 79923
Other names: C. sinensis, oriental liver fluke
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.