STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CARKDATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. (410 aa)    
Predicted Functional Partners:
CSKR_10500s
NAD(P)H-hydrate epimerase.
  
 
 0.944
CSKR_12576s
Uncharacterized protein.
  
 
0.907
sdha
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
      0.620
pol-11
Pol polyprotein.
      
 0.613
fabG
3-oxoacyl-[acyl-carrier-protein] reductase FabG.
      
 0.613
SDH2
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit.
  
  
 0.586
PGM1
Phosphoglucomutase-1.
 
 
    0.570
Rrm1
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
     
 0.567
PNPO
Pyridoxine-5'-phosphate oxidase.
    
 0.560
PNPO-2
Pyridoxine-5'-phosphate oxidase.
    
 0.560
Your Current Organism:
Clonorchis sinensis
NCBI taxonomy Id: 79923
Other names: C. sinensis, oriental liver fluke
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