STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUL5Cullin-5; Belongs to the cullin family. (710 aa)    
Predicted Functional Partners:
Tceb1
Transcription elongation factor B polypeptide 1.
    
 0.994
RBX1A
RING-box protein 1a.
    
 0.973
Roc1a
RING-box protein 1A.
    
 0.973
lrk-1
Leucine-rich repeat serine/threonine-protein kinase 1.
    
 0.970
ari-2
RBR-type E3 ubiquitin transferase.
    
 
 0.964
CSKR_11537s
Uncharacterized protein.
   
 0.943
CAND1
Cullin-associated Nedd8-dissociated protein 1.
    
 0.910
UBE2F
Ubiquitin-conjugating enzyme E2 F; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.887
Cul2
Cullin-2; Belongs to the cullin family.
  
0.883
Dcun1d1
Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.
   
 0.880
Your Current Organism:
Clonorchis sinensis
NCBI taxonomy Id: 79923
Other names: C. sinensis, oriental liver fluke
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.