STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ubc12Nedd8-conjugating enzyme Ubc12. (582 aa)    
Predicted Functional Partners:
UBA3
Nedd8-activating enzyme E1 catalytic subunit.
    
 0.953
Dcun1d1
Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.
    
 0.878
nae1
Nedd8-activating enzyme E1 regulatory subunit.
    
 0.850
CUL1
Cullin-1; Belongs to the cullin family.
    
 0.821
CSKR_517s
Ubiquitin-like modifier-activating enzyme 5.
    
 0.793
Cul3
Cullin-3; Belongs to the cullin family.
    
 0.792
RBX1A
RING-box protein 1a.
    
 0.783
Roc1a
RING-box protein 1A.
    
 0.783
Uba6
Ubiquitin-like modifier-activating enzyme 6.
    
 0.744
UBA1
Ubiquitin-like modifier-activating enzyme 1.
    
 0.744
Your Current Organism:
Clonorchis sinensis
NCBI taxonomy Id: 79923
Other names: C. sinensis, oriental liver fluke
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.