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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
14-3-3zeta14-3-3 protein zeta; Belongs to the 14-3-3 family. (255 aa)    
Predicted Functional Partners:
lrk-1
Leucine-rich repeat serine/threonine-protein kinase 1.
   
 0.935
BRAF
Serine/threonine-protein kinase B-raf.
   
 0.894
FOXO6
Forkhead box protein O6.
    
 0.826
MAP2K1
Dual specificity mitogen-activated protein kinase-like kinase.
   
 0.796
Ksr2
Kinase suppressor of Ras 2.
   
 0.788
Mrpl38
39S ribosomal protein L38.
    
 0.765
cdc25
M-phase inducer phosphatase.
    
 0.762
CDC25C
M-phase inducer phosphatase 3.
    
 0.762
Mark3
Non-specific serine/threonine protein kinase.
    
 0.760
CSKR_10882s
Uncharacterized protein.
    
 0.754
Your Current Organism:
Clonorchis sinensis
NCBI taxonomy Id: 79923
Other names: C. sinensis, oriental liver fluke
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.