STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNKPBifunctional polynucleotide phosphatase/kinase. (394 aa)    
Predicted Functional Partners:
Xrcc1
DNA repair protein XRCC1.
   
 0.963
ENKD1
Enkurin domain-containing protein 1.
    
 0.911
LIG3
DNA ligase.
   
 0.908
TKT
Transketolase.
    
 0.895
Gmd
GDPmannose 4 6-dehydratase.
    
 0.883
IMPA2
Inositol-1-monophosphatase.
   
 
 0.870
LIG4
DNA ligase.
   
 0.864
PGM3
Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.
    
 0.770
PGM2
Phosphoglucomutase-2; Belongs to the phosphohexose mutase family.
    
 0.770
CSKR_740s
Uncharacterized protein.
   
 0.753
Your Current Organism:
Clonorchis sinensis
NCBI taxonomy Id: 79923
Other names: C. sinensis, oriental liver fluke
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.