STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gucy2fGuanylate cyclase. (2232 aa)    
Predicted Functional Partners:
PDE9A
Phosphodiesterase.
    
 0.939
pde-5
Phosphodiesterase.
    
 0.935
PyK
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.925
PKM
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.925
Gyc88E-2
Soluble guanylate cyclase 88E.
  
 
 
0.921
ADCY9-2
Adenylate cyclase type 9.
  
  
 
0.918
PDE6D
Retinal rod rhodopsin-sensitive cGMP 3.
    
 0.917
Pde1c
Phosphodiesterase.
     
 0.917
AK9
Adenylate kinase 9.
     
 0.916
NME1
Nucleoside diphosphate kinase A; Belongs to the NDK family.
    
 0.915
Your Current Organism:
Clonorchis sinensis
NCBI taxonomy Id: 79923
Other names: C. sinensis, oriental liver fluke
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.