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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MDH1BPutative malate dehydrogenase 1B. (610 aa)    
Predicted Functional Partners:
CSKR_5539s
Citrate synthase; Belongs to the citrate synthase family.
  
 0.922
fh
Fumarate hydratase.
  
 0.870
sdha
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  
 0.867
MDH2
Malate dehydrogenase.
   
 0.848
GOT1
Aspartate aminotransferase.
   
 0.838
GOT2
Aspartate aminotransferase.
   
 0.831
Cyb5r4
Cytochrome b5 reductase 4.
  
 
 0.825
PyK
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.820
PKM
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.820
ACLY
ATP-citrate synthase.
  
 0.808
Your Current Organism:
Clonorchis sinensis
NCBI taxonomy Id: 79923
Other names: C. sinensis, oriental liver fluke
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