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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Map4k5Mitogen-activated protein kinase kinase kinase kinase 5. (979 aa)    
Predicted Functional Partners:
MAP3K1
Mitogen-activated protein kinase kinase kinase 1.
   
 0.722
Map3k9
Mitogen-activated protein kinase kinase kinase 9.
    
 0.695
MKL2
MKL/myocardin-like protein 2.
   
  0.617
Grb2
Growth factor receptor-binding protein 2.
    
 
 0.539
grb2-a
Growth factor receptor-bound protein 2-A.
   
 
 0.532
RragB
Ras-related GTP-binding protein B.
    
 
 0.501
SYK
Tyrosine-protein kinase.
   
  0.483
lrk-1
Leucine-rich repeat serine/threonine-protein kinase 1.
    
 0.474
STK4
Serine/threonine-protein kinase 4.
 
      0.473
Map3k7
Mitogen-activated protein kinase kinase kinase 7.
   
 0.469
Your Current Organism:
Clonorchis sinensis
NCBI taxonomy Id: 79923
Other names: C. sinensis, oriental liver fluke
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