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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nae1Nedd8-activating enzyme E1 regulatory subunit. (819 aa)    
Predicted Functional Partners:
UBA3
Nedd8-activating enzyme E1 catalytic subunit.
   
 0.999
UBE2F
Ubiquitin-conjugating enzyme E2 F; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.980
apl-1
Beta-amyloid-like protein.
    
 0.863
ube2m
Nedd8-conjugating enzyme Ubc12.
    
 0.850
Ubc12
Nedd8-conjugating enzyme Ubc12.
    
 0.850
CSKR_1374s
Uncharacterized protein.
    
 0.850
CUL1
Cullin-1; Belongs to the cullin family.
   
 0.844
Atg12
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.
    
 0.815
MOCS2
Molybdopterin synthase catalytic subunit.
  
 0.814
Cul3
Cullin-3; Belongs to the cullin family.
   
 0.804
Your Current Organism:
Clonorchis sinensis
NCBI taxonomy Id: 79923
Other names: C. sinensis, oriental liver fluke
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