STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPC1Niemann-Pick C1 protein. (1631 aa)    
Predicted Functional Partners:
Srebf1
Sterol regulatory element-binding protein 1.
   
0.950
INSIG2
Insulin-induced-like protein.
   
 0.854
npc2
Epididymal secretory protein E1.
    
 0.823
Npc2
Epididymal secretory protein E1.
    
 0.823
NPC2
Epididymal secretory protein E1.
    
 0.823
npc2-2
Epididymal secretory protein E1.
    
 0.823
NPC2-2
Epididymal secretory protein E1.
    
 0.823
NPC2-3
Epididymal secretory protein E1.
    
 0.823
npc2-3
Epididymal secretory protein E1.
    
 0.823
Npc2-2
Epididymal secretory protein E1.
    
 0.823
Your Current Organism:
Clonorchis sinensis
NCBI taxonomy Id: 79923
Other names: C. sinensis, oriental liver fluke
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.