CASP3 protein (Clonorchis sinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CASP3

Caspase-3; Belongs to the peptidase C14A family. (353 aa)

Predicted Functional Partners:

lrk-1

0.986

mib1-2

0.979

apaf1

0.977

APPL2

0.972

CSKR_2411s

0.939

Birc6

0.918

Birc5

0.837

Tep1

0.782

CSKR_158s

0.777

tonsl

0.773

Your Current Organism:

Clonorchis sinensis

NCBI taxonomy Id: 79923
Other names: C. sinensis, oriental liver fluke

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APPL2	Birc6	A0A419PKS9	A0A419QDV6	DCC-interacting protein 13-beta.	Baculoviral IAP repeat-containing protein 6.	0.723
APPL2	CASP3	A0A419PKS9	A0A419PK54	DCC-interacting protein 13-beta.	Caspase-3; Belongs to the peptidase C14A family.	0.972
APPL2	CSKR_158s	A0A419PKS9	A0A3R7CX76	DCC-interacting protein 13-beta.	Uncharacterized protein.	0.972
APPL2	lrk-1	A0A419PKS9	A0A3R7DIY7	DCC-interacting protein 13-beta.	Leucine-rich repeat serine/threonine-protein kinase 1.	0.657
APPL2	tonsl	A0A419PKS9	A0A3R7GYV5	DCC-interacting protein 13-beta.	Tonsoku-like protein.	0.600
Birc5	Birc6	H2KVI0	A0A419QDV6	Baculoviral IAP repeat-containing protein 5.	Baculoviral IAP repeat-containing protein 6.	0.796
Birc5	CASP3	H2KVI0	A0A419PK54	Baculoviral IAP repeat-containing protein 5.	Caspase-3; Belongs to the peptidase C14A family.	0.837
Birc5	CSKR_158s	H2KVI0	A0A3R7CX76	Baculoviral IAP repeat-containing protein 5.	Uncharacterized protein.	0.837
Birc5	CSKR_2411s	H2KVI0	A0A419QF28	Baculoviral IAP repeat-containing protein 5.	Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.523
Birc5	Tep1	H2KVI0	A0A3R7D4S4	Baculoviral IAP repeat-containing protein 5.	Telomerase protein component 1.	0.624
Birc5	apaf1	H2KVI0	A0A3R7EXN6	Baculoviral IAP repeat-containing protein 5.	Apoptotic protease-activating factor 1.	0.797
Birc5	lrk-1	H2KVI0	A0A3R7DIY7	Baculoviral IAP repeat-containing protein 5.	Leucine-rich repeat serine/threonine-protein kinase 1.	0.857
Birc5	tonsl	H2KVI0	A0A3R7GYV5	Baculoviral IAP repeat-containing protein 5.	Tonsoku-like protein.	0.633
Birc6	APPL2	A0A419QDV6	A0A419PKS9	Baculoviral IAP repeat-containing protein 6.	DCC-interacting protein 13-beta.	0.723
Birc6	Birc5	A0A419QDV6	H2KVI0	Baculoviral IAP repeat-containing protein 6.	Baculoviral IAP repeat-containing protein 5.	0.796
Birc6	CASP3	A0A419QDV6	A0A419PK54	Baculoviral IAP repeat-containing protein 6.	Caspase-3; Belongs to the peptidase C14A family.	0.918
Birc6	CSKR_158s	A0A419QDV6	A0A3R7CX76	Baculoviral IAP repeat-containing protein 6.	Uncharacterized protein.	0.918
Birc6	CSKR_2411s	A0A419QDV6	A0A419QF28	Baculoviral IAP repeat-containing protein 6.	Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.720
Birc6	Tep1	A0A419QDV6	A0A3R7D4S4	Baculoviral IAP repeat-containing protein 6.	Telomerase protein component 1.	0.982
Birc6	apaf1	A0A419QDV6	A0A3R7EXN6	Baculoviral IAP repeat-containing protein 6.	Apoptotic protease-activating factor 1.	0.986