STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pde4bcAMP-specific 3. (224 aa)    
Predicted Functional Partners:
AK9
Adenylate kinase 9.
     
 0.910
dnc
Phosphodiesterase.
 
      0.900
ADK
Adenosine kinase.
     
 0.853
Ampd2-2
AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
     
 0.848
AK3
GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
     
 0.848
Enpp5-2
Ectonucleotide pyrophosphatase/phosphodiesterase family member 5.
    
 0.702
enpp4
Bis(5'-adenosyl)-triphosphatase enpp4.
    
 0.702
Cask
Peripheral plasma membrane protein CASK.
    
 0.699
Ampd2
AMP deaminase 2.
     
 0.698
Ampd2-3
AMP deaminase 2.
     
 0.698
Your Current Organism:
Clonorchis sinensis
NCBI taxonomy Id: 79923
Other names: C. sinensis, oriental liver fluke
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.