CSKR_4265s protein (Clonorchis sinensis) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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[Homology]

Score

CSKR_4265s

Kinesin heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1015 aa)

Predicted Functional Partners:

CSKR_13589s

0.971

CSKR_14141s

0.900

DCTN1

0.794

Appbp2

0.743

Klc

0.743

Ttc19

0.743

Klc1

0.743

KLC4

0.743

CSKR_7598s

0.743

CSKR_13451s

0.717

Your Current Organism:

Clonorchis sinensis

NCBI taxonomy Id: 79923
Other names: C. sinensis, oriental liver fluke

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Appbp2	CSKR_13451s	A0A3R7CJ87	A0A419PP04	Amyloid protein-binding protein 2.	Uncharacterized protein.	0.417
Appbp2	CSKR_4265s	A0A3R7CJ87	A0A419QCJ8	Amyloid protein-binding protein 2.	Kinesin heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.743
Appbp2	DCTN1	A0A3R7CJ87	A0A419PW44	Amyloid protein-binding protein 2.	Dynactin subunit 1.	0.417
CSKR_13451s	Appbp2	A0A419PP04	A0A3R7CJ87	Uncharacterized protein.	Amyloid protein-binding protein 2.	0.417
CSKR_13451s	CSKR_13589s	A0A419PP04	A0A3R7EMB6	Uncharacterized protein.	Kinesin light chain.	0.417
CSKR_13451s	CSKR_14141s	A0A419PP04	A0A3R7ERM1	Uncharacterized protein.	Uncharacterized protein.	0.417
CSKR_13451s	CSKR_4265s	A0A419PP04	A0A419QCJ8	Uncharacterized protein.	Kinesin heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.717
CSKR_13451s	CSKR_7598s	A0A419PP04	A0A419QDE2	Uncharacterized protein.	Uncharacterized protein.	0.417
CSKR_13451s	KLC4	A0A419PP04	A0A419PRB3	Uncharacterized protein.	Kinesin light chain 4.	0.417
CSKR_13451s	Klc	A0A419PP04	A0A3R7G6J1	Uncharacterized protein.	Kinesin light chain.	0.417
CSKR_13451s	Klc1	A0A419PP04	A0A419PK99	Uncharacterized protein.	Kinesin light chain 1.	0.417
CSKR_13451s	Ttc19	A0A419PP04	A0A3R7GNH7	Uncharacterized protein.	Tetratricopeptide repeat protein 19.	0.417
CSKR_13589s	CSKR_13451s	A0A3R7EMB6	A0A419PP04	Kinesin light chain.	Uncharacterized protein.	0.417
CSKR_13589s	CSKR_4265s	A0A3R7EMB6	A0A419QCJ8	Kinesin light chain.	Kinesin heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.971
CSKR_13589s	DCTN1	A0A3R7EMB6	A0A419PW44	Kinesin light chain.	Dynactin subunit 1.	0.650
CSKR_13589s	KLC4	A0A3R7EMB6	A0A419PRB3	Kinesin light chain.	Kinesin light chain 4.	0.460
CSKR_13589s	Klc	A0A3R7EMB6	A0A3R7G6J1	Kinesin light chain.	Kinesin light chain.	0.423
CSKR_14141s	CSKR_13451s	A0A3R7ERM1	A0A419PP04	Uncharacterized protein.	Uncharacterized protein.	0.417
CSKR_14141s	CSKR_4265s	A0A3R7ERM1	A0A419QCJ8	Uncharacterized protein.	Kinesin heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.900
CSKR_14141s	DCTN1	A0A3R7ERM1	A0A419PW44	Uncharacterized protein.	Dynactin subunit 1.	0.581

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

15

PPI enrichment p-value:

1.55e-15

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006098

Pentose-phosphate shunt

4 of 11

1.93

0.00010

GO:0046365

Monosaccharide catabolic process

4 of 18

1.71

1.7

0.00017

GO:0005996

Monosaccharide metabolic process

5 of 39

1.47

1.55

0.00010

GO:0019323

Pentose catabolic process

3 of 8

1.94

1.49

0.0011

GO:0044282

Small molecule catabolic process

6 of 60

1.37

1.43

0.00010

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:877

NADPH regeneration, and Gluconate transporter

6 of 8

2.24

4.18

1.95e-09

CL:757

Carbon metabolism, and Pyruvate metabolism

7 of 68

1.38

1.83

1.16e-06

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

thl00040

Pentose and glucuronate interconversions

4 of 12

1.89

2.31

9.85e-06

thl00030

Pentose phosphate pathway

5 of 27

1.63

2.12

4.35e-06

thl01120

Microbial metabolism in diverse environments

8 of 123

1.18

1.49

4.94e-07

thl01200

Carbon metabolism

5 of 65

1.25

1.27

0.00012

thl00480

Glutathione metabolism

2 of 8

1.76

1.01

0.0096

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005856

Cytoskeleton

3 of 20

1.54

0.79

0.0236

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036409

Class II aldolase/adducin N-terminal domain superfamily

3 of 3

2.37

1.57

0.0012

IPR001303

Class II aldolase/adducin N-terminal

3 of 3

2.37

1.57

0.0012

IPR006183

6-phosphogluconate dehydrogenase

2 of 2

2.37

0.79

0.0354

IPR006114

6-phosphogluconate dehydrogenase, C-terminal

2 of 2

2.37

0.79

0.0354

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01007

Class II Aldolase and Adducin N-terminal domain

3 of 3

2.37

2.07

0.00012

SM01350

6-phosphogluconate dehydrogenase, C-terminal domain

2 of 2

2.37

1.23

0.0052

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