STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK1-3Serine/threonine-protein kinase PAK 1. (1061 aa)    
Predicted Functional Partners:
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.811
lrk-1
Leucine-rich repeat serine/threonine-protein kinase 1.
    
 0.741
Rhou
Rho-related GTP-binding protein RhoU.
    
 0.734
ITGB1
Integrin beta.
   
0.734
MAP3K1
Mitogen-activated protein kinase kinase kinase 1.
    
 0.734
racF2
Rho-related protein racF2.
    
 0.734
Rac1
Ras-related C3 botulinum toxin substrate 1.
    
 0.734
Cdc42
Cell division control protein 42.
    
 0.734
NCK1
Cytoplasmic protein NCK1.
    
 0.727
NCK2
Cytoplasmic protein NCK2.
    
 0.727
Your Current Organism:
Clonorchis sinensis
NCBI taxonomy Id: 79923
Other names: C. sinensis, oriental liver fluke
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.