STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
egr1Early growth response protein 1. (623 aa)    
Predicted Functional Partners:
lrk-1
Leucine-rich repeat serine/threonine-protein kinase 1.
    
 0.790
AK9
Adenylate kinase 9.
    
  0.742
unc-89
Muscle M-line assembly protein unc-89.
    
 0.699
unc-89-2
Muscle M-line assembly protein unc-89.
    
 0.699
CSKR_11071s
Uncharacterized protein.
    
 0.699
Sufu
Suppressor of fused-like protein.
    
  0.572
NME8
Thioredoxin domain-containing protein 3-like protein; Belongs to the NDK family.
    
 0.569
CHD4
Chromodomain-helicase-DNA-binding protein 4.
    
 0.563
GTF3C3
General transcription factor 3C polypeptide 3.
    
 0.562
Cyb5r4
Cytochrome b5 reductase 4.
    
  0.554
Your Current Organism:
Clonorchis sinensis
NCBI taxonomy Id: 79923
Other names: C. sinensis, oriental liver fluke
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.