STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
POLE3DNA polymerase epsilon subunit 3. (169 aa)    
Predicted Functional Partners:
Pole
DNA polymerase epsilon catalytic subunit A.
   
 0.999
POLE2
DNA polymerase epsilon subunit 2.
    
 0.997
CHRAC1
Chromatin accessibility complex protein 1.
    
 0.989
Smarca1
Putative global transcription activator SNF2L1.
    
 0.970
Nfyc
Nuclear transcription factor Y subunit gamma.
    
 0.953
Dr1
Protein Dr1.
   
 
 0.940
POLA1
DNA polymerase alpha catalytic subunit.
   
 0.938
Spdya
Speedy protein A.
    
 0.937
BAZ1A
Bromodomain adjacent to zinc finger domain protein 1A.
    
 
 0.920
CLF_102744
DNA polymerase.
   
 0.909
Your Current Organism:
Clonorchis sinensis
NCBI taxonomy Id: 79923
Other names: C. sinensis, oriental liver fluke
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.