STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNP-2Purine nucleoside phosphorylase. (330 aa)    
Predicted Functional Partners:
apt
Adenine phosphoribosyltransferase.
  
 
 0.947
ADK
Adenosine kinase.
    
 0.941
uprt
Uracil phosphoribosyltransferase-like protein.
  
 
 0.937
Upp2
Uridine phosphorylase 2.
    
 0.932
CSKR_9866s
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
    
 0.931
HGPRT-2
Hypoxanthine-guanine phosphoribosyltransferase.
  
 0.930
NAMPT
Nicotinamide phosphoribosyltransferase.
    
 0.920
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
  
 
 0.916
sirt5
NAD-dependent protein deacylase sirtuin-5.
    
 0.912
Nt5c2
Cytosolic purine 5'-nucleotidase.
     
 0.912
Your Current Organism:
Clonorchis sinensis
NCBI taxonomy Id: 79923
Other names: C. sinensis, oriental liver fluke
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.