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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL57663.1Ferredoxin. (76 aa)    
Predicted Functional Partners:
hisB
Predicted imidazoleglycerol-phosphate dehydratase.
       0.865
tfrA
Thiol:fumarate reductase, subunit A; Catalyzes the reduction of fumarate with reduced coenzyme M (CoM-S-H) and coenzyme B (CoB-S-H). In vitro, is able to reduces fumarate with reduced benzyl viologen, oxidize CoM-S-H and CoB-S-H to CoM-S-S-CoB with methylene blue, and reduce CoM-S-S-CoB with reduced benzyl viologen. The enzyme has specificity for the two thiol compounds as the CoB--CoM heterodisulfide reductase. The enzyme is very sensitive to oxygen; Belongs to the FAD-dependent oxidoreductase 2 family.
  
 
 0.833
ADL57664.1
Predicted transporter protein.
  
  
 0.797
ADL57743.1
Predicted NADH dehydrogenase.
   
 
 0.778
ADL57665.1
Predicted transporter protein.
       0.616
ADL58711.1
Conserved hypothetical protein; Belongs to the DegT/DnrJ/EryC1 family.
 
     0.611
ADL59185.1
Predicted ATP-dependent DNA ligase.
  
     0.571
ADL58149.1
Predicted glutamate synthase, large subunit; Belongs to the glutamate synthase family.
  
  
 0.563
ADL58283.1
Tungsten formylmethanofuran dehydrogenase, subunit C related protein.
 
    0.543
cdhB1
acetyl-CoA decarbonylase/synthase, subunit epsilon; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD-mediated CO oxidation. Belongs to the CdhB family.
 
   
 0.540
Your Current Organism:
Methanothermobacter marburgensis
NCBI taxonomy Id: 79929
Other names: M. marburgensis str. Marburg, Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133), Methanobacterium thermoautotrophicum str. Marburg, Methanothermobacter marburgensis str. Marburg, Methanothermobacter marburgensis strain Marburg
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