Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sfsAPredicted DNA-binding protein; Belongs to the SfsA family. (232 aa)    
Predicted Functional Partners:
ADL58616.1
Conserved hypothetical protein.
     0.757
ADL58621.1
TOPRIM domain-containing protein.
       0.617
xerA
Predicted site-specific recombinase/integrase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Belongs to the 'phage' integrase family. XerA subfamily.
       0.617
hisH
Predicted imidazole glycerol phosphate synthase, subunit H; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
 
     0.601
ADL57716.1
Predicted nucleotidyl transferase.
 
     0.573
ADL57715.1
Predicted nitrogenase molybdenum-iron protein.
       0.518
ADL57718.1
HypE-related protein.
       0.518
ADL57719.1
Conserved hypothetical protein.
       0.505
thsA
Thermosome, subunit alpha (chaperonin subunit); Belongs to the TCP-1 chaperonin family.
      
 0.439
thsB
Thermosome, subunit beta (chaperonin subunit); Belongs to the TCP-1 chaperonin family.
      
 0.439
Your Current Organism:
Methanothermobacter marburgensis
NCBI taxonomy Id: 79929
Other names: M. marburgensis str. Marburg, Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133), Methanobacterium thermoautotrophicum str. Marburg, Methanothermobacter marburgensis str. Marburg, Methanothermobacter marburgensis strain Marburg
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