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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fwdCTungsten formylmethanofuran dehydrogenase, subunit C; Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). Can only oxidize formylmethanofuran. This enzyme is oxygen-labile. (270 aa)    
Predicted Functional Partners:
fwdD
Tungsten formylmethanofuran dehydrogenase, subunit D.
 
 
 0.999
fwdA
Tungsten formylmethanofuran dehydrogenase, subunit A.
 
 
 0.999
fwdB
Tungsten formylmethanofuran dehydrogenase, subunit B.
 
 
 0.999
mcrA
Methyl-coenzyme M reductase I, subunit alpha; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. Neither N-6- mercaptohexanoylthreonine phosphate (H-S-HxoTP) nor N-8- mercaptooctanoylthreonine phosphate (H-SOcoTP) nor any other thiol compound such as CoA or CoM [...]
     
 0.999
mcrD
Methyl-coenzyme M reductase I, subunit delta.
     
 0.999
fwdF
Tungsten formylmethanofuran dehydrogenase, subunit F.
  
 
 0.998
fwdG
Tungsten formylmethanofuran dehydrogenase, subunit G.
 
   0.991
fdhA1
Predicted formate dehydrogenase, alpha chain.
  
 0.978
ehaQ
Energy-converting hydrogenase A, subunit Q.
  
 
 0.973
fmdB
Molybdenum containing formylmethanofuran dehydrogenase, subunit B.
 
 
 0.929
Your Current Organism:
Methanothermobacter marburgensis
NCBI taxonomy Id: 79929
Other names: M. marburgensis str. Marburg, Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133), Methanobacterium thermoautotrophicum str. Marburg, Methanothermobacter marburgensis str. Marburg, Methanothermobacter marburgensis strain Marburg
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