STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nifDNitrogenase molybdenum-iron protein, alpha chain; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation. (470 aa)    
Predicted Functional Partners:
nifH1
Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
 0.999
nifK1
Nitrogenase molybdenum-iron protein, beta chain; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation; Belongs to the NifD/NifK/NifE/NifN family.
 
 0.999
nifN
Nitrogenase iron-molybdenum cofactor biosynthesis protein NifN; Belongs to the NifD/NifK/NifE/NifN family.
 
0.997
nifH2
Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
 
 0.978
nifE
Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE; This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor); Belongs to the NifD/NifK/NifE/NifN family.
 
  
0.966
nifX
Nitrogenase iron-molybdenum cofactor biosynthesis protein NifX.
 
  
 0.966
nifI1
Nitrogen regulatory protein NifI1; Could be involved in the regulation of nitrogen fixation.
 
 
 0.965
glnA
Glutamine synthetase.
   
 
 0.931
nifB
Archaeal nitrogenase iron-molybdenum cofactor biosynthesis protein NifB; Radical SAM protein.
 
  
 0.924
hcp
Hydroxylamine reductase-related protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
     
 0.905
Your Current Organism:
Methanothermobacter marburgensis
NCBI taxonomy Id: 79929
Other names: M. marburgensis str. Marburg, Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133), Methanobacterium thermoautotrophicum str. Marburg, Methanothermobacter marburgensis str. Marburg, Methanothermobacter marburgensis strain Marburg
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.