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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ftsZPredicted cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (381 aa)    
Predicted Functional Partners:
hmgA
3-hydroxy-3-methylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.
      
 0.994
hisS
histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
  
 0.923
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
 
  
 0.886
ADL58993.1
Predicted rod shape-determining protein.
  
 
 0.872
dnaK
Chaperone DnaK; Acts as a chaperone.
   
 
 0.857
argS
arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
   
 0.852
ehbL
Energy-converting hydrogenase B, subunit L.
  
  
 0.838
secE
SecE-related protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
 
  
 0.829
thrS
threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
  
 0.800
ehaB
Energy-converting hydrogenase A, subunit B.
      
 0.791
Your Current Organism:
Methanothermobacter marburgensis
NCBI taxonomy Id: 79929
Other names: M. marburgensis str. Marburg, Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133), Methanobacterium thermoautotrophicum str. Marburg, Methanothermobacter marburgensis str. Marburg, Methanothermobacter marburgensis strain Marburg
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