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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acsA2Acetyl-coenzyme A synthetase. (548 aa)    
Predicted Functional Partners:
atoB
acetyl-CoA acetyltransferase.
  
 
 0.958
leuA1
Predicted 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.933
leuA2
Predicted 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.933
porD
Pyruvate synthase, subunit D.
  
 
 0.926
porA1
Pyruvate synthase, subunit A.
  
 
 0.923
porC
Pyruvate synthase, subunit C.
  
 
 0.923
porA2
Predicted pyruvate flavodoxin/ferredoxin oxidoreductase, subunit alpha.
  
 
 0.923
korA
2-oxoglutarate synthase, subunit alpha.
  
 
 0.923
cdhC
acetyl-CoA decarbonylase/synthase, subunit beta; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family.
   
 
 0.922
cdhE
acetyl-CoA decarbonylase/synthase, subunit gamma; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).
   
 
 0.921
Your Current Organism:
Methanothermobacter marburgensis
NCBI taxonomy Id: 79929
Other names: M. marburgensis str. Marburg, Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133), Methanobacterium thermoautotrophicum str. Marburg, Methanothermobacter marburgensis str. Marburg, Methanothermobacter marburgensis strain Marburg
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