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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL58292.1Predicted sugar phosphate isomerase / epimerase. (247 aa)    
Predicted Functional Partners:
ADL58291.1
Predicted ATPase.
       0.923
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
       0.922
ADL58858.1
Predicted dehydrogenase.
  
  
 0.831
hisS
histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.814
fno
F420H2:NADP oxidoreductase; Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions; Belongs to the F420-dependent NADP reductase family.
  
    0.799
phi2
Predicted 3-hexulose-6-phosphate isomerase.
  
    0.750
ehaT
Energy-converting hydrogenase T, subunit T; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.657
endA
Predicted tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
       0.650
ADL58012.1
Predicted ribokinase; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.645
ADL58256.1
Predicted DNA lyase.
     
 0.635
Your Current Organism:
Methanothermobacter marburgensis
NCBI taxonomy Id: 79929
Other names: M. marburgensis str. Marburg, Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133), Methanobacterium thermoautotrophicum str. Marburg, Methanothermobacter marburgensis str. Marburg, Methanothermobacter marburgensis strain Marburg
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